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Updated: Jul 16, 2026
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Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
Published on: April 11, 2012
Monostotic fibrous dysplasia
Enzo A Cento1, Laurie M Lomasney, Terrence C Demos
1Department of Radiology, Loyola University, Medical Center, Maywood, IL 60153, USA.
Orthopedics
|February 28, 2007
Summary
Fibrous dysplasia is usually a benign, solitary bone lesion. Early recognition of its imaging features, like the "ground-glass" pattern, aids diagnosis and management.
Area of Science:
- Orthopedic Surgery
- Radiology
- Medical Genetics
Background:
- Fibrous dysplasia is a benign bone disorder where normal bone is replaced by fibrous tissue.
- It most commonly presents as a monostotic (single bone) lesion, often asymptomatic.
- Polyostotic (multiple bones) fibrous dysplasia can be associated with syndromes like McCune-Albright syndrome.
Observation:
- The characteristic imaging appearance includes a "ground-glass" pattern of mineralization.
- Medullary expansion of the affected bone is another common finding.
- Radiographic and CT imaging are crucial for diagnosis.
Findings:
- Monostotic fibrous dysplasia is typically an incidental finding in asymptomatic individuals.
- Polyostotic forms and associated syndromes can lead to significant morbidity.
- Surgical intervention may be required for complications and deformities.
Implications:
- Familiarity with fibrous dysplasia imaging can lead to earlier diagnosis and prevent unnecessary investigations.
- Accurate diagnosis and understanding of potential syndromes are vital for patient management.
- Imaging plays a key role in treatment planning and monitoring disease progression.
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