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An external cause for 'idiopathic' pachymeningitis?
K Vermeirsch1, B Dubois, R Sciot
1Departments of Rheumatology, Neurology and Pathology, University Hospital K.U. Leuven.
Abstract:
In a 67-year-old man with a history of professional asbestos exposure and persistent headaches since one year, a diagnosis of idiopathic pachymeningitis was made. IHCP (idiopathic hypertrophic cranial pachymeningitis) is in literature referred to as one of the presentations of Multifocal Idiopathic Fibrosclerosis or MIF, representing a group of fibro-inflammatory and pathologically similar diseases, including also retroperitoneal fibrosis, mediastinal fibrosis and sclerosing cholangitis. Since recent literature links asbestos exposure to a risk of development of retroperitoneal fibrosis, the present case suggests to focus in future research of IHCP on possible external causes.
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