Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Minimus: a fast, lightweight genome assembler.

Daniel D Sommer1, Arthur L Delcher, Steven L Salzberg

  • 1Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA. dsommer@umiacs.umd.edu <dsommer@umiacs.umd.edu>

BMC Bioinformatics
|February 28, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Testing the reliability of AI-generated protein structures.

bioRxiv : the preprint server for biology·2026
Same author

TIPP-SD: A new method for species detection in microbiomes.

PLoS computational biology·2026
Same author

Comparison of unbiased metagenomic next generation sequencing to targeted multiplex diagnostic assays for the detection of respiratory viruses.

PloS one·2026
Same author

Double humanised lupus mouse model with human immune system and faecal microbiota from patients with SLE.

Lupus science & medicine·2026
Same author

Evidence of off-target probe binding affecting 10x Genomics Xenium gene panels compromise accuracy of spatial transcriptomic profiling.

eLife·2026
Same author

A reference genome sequence for the exceptionally long-lived Great Basin bristlecone pine, Pinus longaeva.

G3 (Bethesda, Md.)·2026
Same journal

OpenIMC: an open-source platform for analyzing single-cell and spatial proteomics by imaging mass cytometry.

BMC bioinformatics·2026
Same journal

NAP: an open source pipeline for cross-domain microbiome profiling using Nanopore sequencing-derived amplicon data.

BMC bioinformatics·2026
Same journal

SurvGME: an R package for survival analysis with graphical and measurement error models.

BMC bioinformatics·2026
Same journal

SimMapNet: a Bayesian framework for gene regulatory network inference using gene ontology similarities as external hint.

BMC bioinformatics·2026
Same journal

Dual channel drug-drug interactions extraction based on cross attention.

BMC bioinformatics·2026
Same journal

FeSseqdb: a curated sequence-level database and interpretable machine learning framework for identifying iron-sulfur proteins.

BMC bioinformatics·2026
See all related articles

Minimus is a new, simplified genome assembler designed for smaller sequencing projects. It offers faster, more flexible assembly with fewer errors compared to complex tools, making it ideal for viral, gene, and BAC clone assemblies.

Area of Science:

  • Genomics
  • Bioinformatics
  • Computational Biology

Background:

  • Genome assemblers have become increasingly complex to handle large-scale sequencing projects.
  • Simpler assemblers are needed for common tasks, requiring less memory and easier installation.

Purpose of the Study:

  • To develop and evaluate the Minimus assembler for small-scale genome assembly tasks.
  • To assess Minimus' suitability as a component in larger assembly pipelines.

Main Methods:

  • Development of the Minimus assembler.
  • Testing Minimus on various assembly problems, including viral genomes, genes, BAC clones, and bacterial genomes.

Main Results:

  • Minimus performs well on small assembly tasks, showing fewer errors than existing software.

Related Experiment Videos

  • Assembly of bacterial genomes indicates Minimus' potential as a pipeline component, though it produces more fragmented results.

    • Conclusions:

    • Minimus is faster and more flexible than existing tools for small genomes and assembly tasks.
    • Its modular design makes it suitable for complex assembly pipelines.
    • Minimus is available as open-source software within the AMOS project.