Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Response sequence difficulty in an incremental repeated acquisition (learning) procedure.

L K M Wright1, M G Paule

  • 1Division of Neurotoxicology, National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079-9502, USA. linnzi.wright@okstate.edu

Behavioural Processes
|February 28, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Discontinuation of methylphenidate after long-term exposure in nonhuman primates.

Neurotoxicology and teratology·2023
Same author

MicroPET/CT assessment of neurochemical effects in the brain after long-term methylphenidate treatment in nonhuman primates.

Neurotoxicology and teratology·2021
Same author

Minimally invasive biomarkers of general anesthetic-induced developmental neurotoxicity.

Neurotoxicology and teratology·2016
Same author

MicroPET/CT assessment of FDG uptake in brain after long-term methylphenidate treatment in nonhuman primates.

Neurotoxicology and teratology·2016
Same author

Caramiphen edisylate as adjunct to standard therapy attenuates soman-induced seizures and cognitive deficits in rats.

Neurotoxicology and teratology·2014
Same author

Lack of effect of prefeeding on food-reinforced temporal response differentiation and progressive ratio responding.

Behavioural processes·2014

Incremental repeated acquisition (IRA) procedures reveal that learning response sequences depends on lever proximity. Adjacent lever sequences are easier to learn than non-adjacent ones, impacting behavioral research.

Area of Science:

  • Behavioral neuroscience
  • Cognitive psychology

Background:

  • Incremental repeated acquisition (IRA) is a procedure where subjects learn increasingly complex behavioral response sequences.
  • Understanding factors influencing learning difficulty in IRA is crucial for experimental design.

Purpose of the Study:

  • To determine if certain response sequences are inherently more difficult to acquire than others within IRA procedures.
  • To identify potential confounds in drug and experimental manipulation studies due to sequence difficulty.

Main Methods:

  • Analysis of control data from two large rodent studies involving IRA.
  • Classification of response sequences into easy, moderate, and hard difficulty levels based on accuracy.

Main Results:

Related Experiment Videos

  • Response sequences requiring actions on adjacent levers were acquired with higher accuracy than those on non-adjacent levers.
  • Sequences involving two levers were easier to learn than those requiring all three levers.

    • Conclusions:

    • Response sequence difficulty in IRA is influenced by lever arrangement, specifically adjacency.
    • Sequence difficulty must be accounted for to accurately interpret results from drug and experimental manipulation studies using IRA.