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Updated: Jan 27, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Suicide by multidrug ingestion: hypothesis on the role played by the self-administration of activated charcoal
D R Vantaggiato1, N De Giovanni
1Istituto di Medicina Legale e delle Assicurazioni, Rome, Italy. daniela.vantaggiato@rm.unicatt.it
Abstract:
A fatal suicidal ingestion of drugs, together with activated charcoal, is reported. The death occurred 31 hours after the self-administration. The autopsy revealed a large amount of gastric content that appeared to be a compact mass of black color. Toxicologic analyses showed the presence of toxic levels of desalkylflurazepam and trazodone; metamizole and pridinol were also detected. The obtained results supported the hypothesis of a death due to acute intoxication delayed by the self-administration of activated charcoal, which elimination was probably hindered by the action of pridinol.
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