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Related Experiment Videos

Thromboembolism following multiple trauma.

M M Knudson1, J A Collins, S B Goodman

  • 1Department of Surgery, University of California, San Francisco General Hospital 94110.

The Journal of Trauma
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

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Thromboembolic complications in trauma patients are common. Low-dose heparin (LDH) and sequential compression devices (SCDs) showed similar safety profiles, with LDH having a slightly lower incidence of deep venous thrombosis (DVT) and pulmonary embolism (PE).

Area of Science:

  • Trauma and Emergency Medicine
  • Vascular Surgery
  • Critical Care Medicine

Background:

  • The incidence of thromboembolic complications after multiple trauma remains unknown.
  • No universally safe and effective prophylaxis method exists for seriously injured patients.
  • Deep venous thrombosis (DVT) and pulmonary embolism (PE) are significant risks in trauma.

Purpose of the Study:

  • To compare the efficacy and safety of low-dose heparin (LDH) versus sequential compression devices (SCDs) for thromboembolism prophylaxis in trauma patients.
  • To identify risk factors associated with thromboembolic complications in this patient population.

Main Methods:

  • Prospective study involving 113 trauma patients.
  • Patients received either LDH (5,000 U SC q12h) or SCDs upon admission.

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  • Duplex venous ultrasound, V/Q scans, and pulmonary angiograms were used for diagnosis.

    • Main Results:

    • 12 patients (10.6%) experienced thromboembolic complications: 9/76 (12%) in SCD group, 3/37 (8%) in LDH group.
    • Complications included DVT only, PE without DVT, and combined DVT and PE.
    • Older age, longer immobilization, more transfusions, and admission clotting abnormalities were linked to complications.

    Conclusions:

    • Both LDH and SCDs appear safe for prophylaxis in trauma patients.
    • LDH demonstrated a slightly lower incidence of DVT/PE compared to SCDs.
    • An identifiable subgroup of high-risk trauma patients warrants prophylaxis and close DVT/PE surveillance.