Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Peripheral Blood Lymphocytosis Reflecting an Underlying Thymoma.

American journal of hematology·2026
Same author

Kelp gametophytes upregulate photosynthetic bicarbonate (HCO<sub>3</sub> <sup>-</sup>) utilization in response to irradiance and temperature.

Journal of phycology·2026
Same author

Systemic clinical-grade recombinant decorin reduces disease burden and fibrosis in advanced recessive dystrophic epidermolysis bullosa.

Molecular therapy. Advances·2026
Same author

Striking Bone Marrow Plasmacytosis Resulting From Visceral Leishmaniasis.

American journal of hematology·2026
Same author

Compound Heterozygosity for Hemoglobin S and Hemoglobin LuLu Island.

American journal of hematology·2026
Same author

Moving parts: toddler presenting with new movement disorder.

Archives of disease in childhood. Education and practice edition·2026

Related Experiment Video

Updated: Jul 16, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
03:23

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

Case 32. Eosinophilia: reactive or neoplastic?

Sarah Fletcher1, Saad Abdalla, Matthew Edwards

  • 1Department of Haematology, St Mary's Hospital, London, UK.

Leukemia & Lymphoma
|February 28, 2007
PubMed
Summary

Eosinophilic leukemia was suspected in a patient with high eosinophil counts and anemia. Further tests confirmed the diagnosis, highlighting the importance of comprehensive evaluation.

Area of Science:

  • Hematology
  • Oncology
  • Genetics

Background:

  • Eosinophilic leukemia is a rare hematologic malignancy characterized by excessive eosinophil production.
  • Early diagnosis is crucial for effective treatment and improved patient outcomes.

Observation:

  • A patient presented with unexplained eosinophilia and mild macrocytic anemia.
  • Initial findings suggested a potential diagnosis of eosinophilic leukemia.

Findings:

  • Genetic analysis revealed trisomy 8, a chromosomal abnormality associated with certain myeloid neoplasms.
  • Subsequent clinical course and diagnostic tests confirmed the diagnosis of eosinophilic leukemia.

Implications:

  • This case underscores the importance of integrating clinical, laboratory, and genetic findings for accurate diagnosis of rare hematologic disorders.

Related Experiment Videos

Last Updated: Jul 16, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
03:23

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

  • Trisomy 8 can be an important indicator in the diagnostic workup of eosinophilia.
  • Accurate diagnosis facilitates timely and appropriate therapeutic interventions.