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S-layers as a tool kit for nanobiotechnological applications.
Uwe B Sleytr1, Carina Huber, Nicola Ilk
1Center for NanoBiotechnology, University of Natural Resources and Applied Life Sciences Vienna, Gregor Mendel Strasse 33, A-1180 Vienna, Austria. uwe.sleytr@boku.ac.at
FEMS Microbiology Letters
|March 1, 2007
Summary
Bacterial cell surface layers (S-layers) self-assemble into crystalline arrays, serving as versatile building blocks for advanced nanobiotechnology and biomimetic applications.
Area of Science:
- Microbiology
- Nanotechnology
- Biomaterials
Background:
- Crystalline bacterial cell surface layers (S-layers) are common in bacteria and archaea.
- Isolated S-layer proteins self-assemble into ordered arrays on various surfaces and lipid structures.
Purpose of the Study:
- To review the fundamental principles of S-layer proteins.
- To explore the application potential of S-layers in nanobiotechnology and biomimetics.
Main Methods:
- Review of existing literature on S-layer protein self-assembly.
- Analysis of S-layer applications in constructing supramolecular structures and devices.
Main Results:
- S-layer proteins self-assemble into monomolecular crystalline arrays.
- S-layers function as adaptable building blocks for 'bottom-up' assembly of functional nanomaterials.
Conclusions:
- S-layers are highly versatile for biomolecular construction kits.
- S-layers offer innovative approaches for nanobiotechnology and biomimetic device development.
