Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Association Areas of the Cortex01:21

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Alzheimer Disease ll: Pathophysiology01:23

Alzheimer Disease ll: Pathophysiology

Alzheimer disease involves structural changes in the brain that begin long before symptoms appear. The most distinctive features are extracellular neuritic plaques and intracellular neurofibrillary tangles.Neuritic plaques form in the cerebral cortex and around blood vessels. These plaques contain a dense core of beta-amyloid (Aβ)—a toxic protein fragment that clumps outside neurons. The core is surrounded by damaged neuronal extensions, as well as reactive astrocytes and microglia. Abnormal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

[Guidelines for the Management of Secondary Hypogammaglobulinemia in Multiple Sclerosis Patients on Anti-CD20 Monoclonal Antibody Therapy].

Acta medica portuguesa·2026
Same author

Guardian 4-Associated Contact Dermatitis in a Teenager With Multiple Sensitizations.

Dermatitis : contact, atopic, occupational, drug·2026
Same author

Pseudotumoral multiple sclerosis: unveiling its clinical and imaging characteristics.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same author

Correction: Home-based Rehabilitation With A Novel Digital Biofeedback System versus Conventional In-person Rehabilitation after Total Knee Replacement: a feasibility study.

Scientific reports·2026
Same author

Technological solutions for multiple sclerosis: a scoping review.

International journal of medical informatics·2026
Same author

Further Validation and Threshold Determination of Brazilian-Portuguese Version of the CU-Q2oL Questionnaire.

The British journal of dermatology·2026

Related Experiment Video

Updated: Jul 16, 2026

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

[Frontotemporal dementia].

Joana Guimarães1, Rosália Fonseca, Carolina Garrett

  • 1Serviço de Neurologia, Hospital de São João, Porto, Portugal.

Acta Medica Portuguesa
|March 3, 2007
PubMed
Summary

Frontotemporal dementia (FTD) is a significant cause of dementia, often misdiagnosed. This study reviews FTD

Area of Science:

  • Neurology
  • Neuroscience
  • Geriatrics

Context:

  • Frontotemporal dementia (FTD) represents 8-17% of dementia deaths before age 70.
  • FTD presents with diverse clinical symptoms, including behavioral changes and language impairments.
  • Diagnostic criteria for FTD remain a subject of debate in scientific literature.

Purpose:

  • To provide a comprehensive overview of frontotemporal dementia (FTD).
  • To focus on clinical, imagiological, pathological, and genetic aspects of FTD.
  • To characterize patients managed at a hospital's Dementia Outpatient Clinical Care unit.

Summary:

  • This review synthesizes current knowledge on FTD, covering its clinical, imaging, pathological, and genetic dimensions.
  • A retrospective analysis correlated clinical presentations with imagiological and neuropsychological findings in a patient cohort.

Related Experiment Videos

Last Updated: Jul 16, 2026

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

  • The study highlights the importance of accurate FTD diagnosis, addressing potential misdiagnoses.

    • Impact:

    • Enhances understanding of FTD's complex presentations and diagnostic challenges.
    • Provides insights into patient characteristics and disease progression in a clinical setting.
    • Aims to improve the recognition and diagnosis of frontotemporal dementia.