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Updated: Jul 16, 2026

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
SO3(2-)-based chemiluminescence in unbuffered solution with ClO2 as oxidant and its analytical application
Baoxin Li1, Qingwen Deng, Chunli Xu
1Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Materials Science, Shaanxi Normal University, Xi'an, PR China. libx29@hotmail.com
Abstract:
In this paper, SO3(2-)-chemiluminescence (CL) system in unbuffered solution with ClO2 as oxidant is proposed. ClO2 could oxidize sulfite in unbuffered solution to produce CL emission, and riboflavin could sensitize the ClO2-SO3(2-)-based CL system. The ClO2-SO3(2-)-riboflavin CL reaction was chosen as a model system and explored the possibility of SO3(2-)-based CL system in unbuffered solution. Compared with the reported SO3(2-)-based CL system in strong acid media, the proposed CL system owns its advantages. Combined with flow-injection analysis, the proposed CL system was applied to measurement of riboflavin in pharmaceuticals.
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