Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pathophysiology of obesity.

G A Bray1

  • 1Pennington Biomedical Research Center, Baton Rouge, LA 70808.

The American Journal of Clinical Nutrition
|February 1, 1992
PubMed
Summary

Obesity poses significant health risks, with Body Mass Index (BMI) classifying individuals into risk categories. Class IV (BMI > 40 kg/m2) indicates very high risk and is primary for surgical consideration.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of pioglitazone on body composition and bone density in subjects with prediabetes in the ACT NOW trial.

Diabetes, obesity & metabolism·2013
Same author

Diet type and changes in food cravings following weight loss: findings from the POUNDS LOST Trial.

Eating and weight disorders : EWD·2012
Same author

Effect of diet composition on energy expenditure during weight loss: the POUNDS LOST Study.

International journal of obesity (2005)·2011
Same author

Sensitivity to the satiating effects of exendin 4 is decreased in obesity-prone Osborne-Mendel rats compared to obesity-resistant S5B/Pl rats.

International journal of obesity (2005)·2010
Same author

Effect of a 3-day high-fat feeding period on carbohydrate balance and ad libitum energy intake in humans.

International journal of obesity (2005)·2010
Same author

Determinants of glucose tolerance in impaired glucose tolerance at baseline in the Actos Now for Prevention of Diabetes (ACT NOW) study.

Diabetologia·2009

Area of Science:

  • Clinical Medicine
  • Public Health

Background:

  • Individuals exceeding 100 kg represent a small population segment but face substantial health risks.
  • Excess body weight is a major contributor to severe health complications.

Purpose of the Study:

  • To propose a Body Mass Index (BMI) classification system for categorizing obesity risk.
  • To identify specific health risks associated with different BMI classes, particularly severe obesity.

Main Methods:

  • Classification of individuals into five classes (Class 0-IV) based on Body Mass Index (BMI) ranges (kg/m2).
  • Description of associated health risks for each BMI class.

Main Results:

  • Class 0 (BMI 20-25): Not obese.
  • Class I (BMI 25-30): Low obesity risk.
  • Class II (BMI 30-35): Moderate obesity risk.
  • Class III (BMI 35-40): High obesity risk.
  • Class IV (BMI > 40): Very high obesity risk, primary candidates for bariatric surgery.

Conclusions:

  • The proposed BMI classification effectively stratifies obesity-related health risks.
  • Class IV obesity is linked to severe conditions including cardiomyopathy, sleep apnea, hormonal dysfunction, acanthosis nigricans, and osteoarthritis.
  • Class IV individuals require significant medical attention and are prioritized for surgical interventions.

Related Experiment Videos