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Purpuric-like rash as cutaneous eruptions in parvovirus B19 infection in Thai infant
Susheera Chatproedprai1, Pitirat Boonsuk, Siriwan Wananukul
1Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand. susheerac@hotmail.com
Insights
A child
Area of Science:
- Pediatrics
- Infectious Diseases
- Dermatology
Background:
- Fever, rash, and diarrhea are common symptoms in children, necessitating a broad differential diagnosis.
- Purpuric rashes can indicate serious underlying conditions, requiring prompt medical evaluation.
Observation:
- An 8-month-old girl presented with fever, rash, and diarrhea.
- Physical examination revealed distinct brownish-black, purpuric-like rashes on the face, arms, and legs, accompanied by lymphadenopathy.
Findings:
- Laboratory tests indicated mild anemia and thrombocytopenia.
- Polymerase chain reaction (PCR) confirmed the presence of parvovirus B19 DNA in the serum.
Implications:
- Parvovirus B19 infection can present with diverse dermatological manifestations, including purpuric rashes.
- Clinicians should consider parvovirus B19 in the differential diagnosis of febrile illnesses with purpuric eruptions in pediatric patients.
- The patient experienced an uneventful recovery with supportive care, highlighting the importance of early identification and management.
Abstract:
An 8-month-old girl presented with fever, rash, and diarrhea. Physical examination revealed multiple well-circumscribed, brownish-black, purpuric-like rashes on the face, arms, and legs with cervical and suboccipital lymphadenopathy. Laboratory findings showed mild anemia with thrombocytopenia and positive polymerase chain reaction for parvovirus 819 DNA in the serum. The patient recovered uneventfully with symptomatic and supportive treatment. Since the infection can manifest in many dermatological patterns, it should also be included in the differential diagnosis of febrile illness with purpuric rash in children.
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