Related Experiment Video
Updated: Jul 16, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
[Depression and clinical illness: comorbidity in a geriatric outpatient clinic]
Meirelayne Borges Duarte1, Marco Antônio Vasconcelos Rego
1Faculdade de Medicina, Universidade Federal da Bahia, Avenida Reitor Miguel Calmon s/n, Salvador, BA 40110-100, Brazil. meirelayne@reim.com.br
Abstract:
The aim of this study was to investigate the association between depression and clinical illness among a group of elderly in the city of Salvador, Bahia, Brazil. The study population included 1,120 individuals over 60 years of age treated at a geriatric outpatient clinic. Crude and stratified prevalence ratios were calculated. Data were stratified by gender, age, and nutritional status. Ninety-five percent of the sample presented at least one chronic disease, the most frequent being hypertension (62.2%), osteoarthritis (40%), and urinary incontinence (35%). Depression was diagnosed in 23.4%, more commonly among women (PR = 1.28; 95%CI: 0.99-1.65) and those under 75 years (PR = 1.24; 95%CI: 1.00-1.53). There was an association between number of chronic diseases (> 3) and depression (PR = 1.31; 95%CI: 1.04-1.66). Parkinson's disease was associated with depression, more evident among females (PR = 1.59; 95%CI: 1.05-2.41) and in the 70-79-year age group (PR = 2.02; 95%CI: 1.28-3.20). The study demonstrates an association between depression and chronic comorbidity. Since many elderly present multiple chronic diseases, health professionals should be alert to the possibility of depressive symptoms in these patients.
Related Concept Videos
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Depressive Disorders: MDD and Dysthymia
Depression: Overview
Long-term Depression
Long-term Depression
Calcium Ion Concentration Mechanism
If over time, all...
Pharmacodynamics in Geriatric Patients: Effects of Age
