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Related Experiment Video

Updated: Jul 16, 2026

Tension-Free Weight-Bearing Model of Steroid-Induced Osteonecrosis of Femoral Head in Rats
05:55

Tension-Free Weight-Bearing Model of Steroid-Induced Osteonecrosis of Femoral Head in Rats

Published on: September 27, 2024

[Glucocorticoid induced osteoporosis].

U Lange1, U Müller-Ladner

  • 1Abt. Rheumatologie, Klinische Immunologie, Physikalische Medizin und Osteologie, Kerckhoff-Klinik, Benekestrasse 2-8, 61231 Bad Nauheim. U.Lange@kerckhoff-klinik.de

Zeitschrift Fur Rheumatologie
|March 6, 2007
PubMed
Summary

Secondary osteoporosis, often caused by medications like glucocorticoids, affects many patients and leads to fractures. This review updates guidelines for glucocorticoid-induced osteoporosis management.

Area of Science:

  • Endocrinology
  • Bone Metabolism
  • Pharmacology

Context:

  • Secondary osteoporosis affects 5% of osteoporosis patients, contributing to 20% of fractures.
  • Glucocorticoid-induced osteoporosis is the most prevalent form of secondary osteoporosis.
  • Chronic inflammatory diseases necessitating glucocorticoid therapy are significant risk factors for osteoporosis.

Purpose:

  • To present current data on glucocorticoid-induced osteoporosis.
  • To provide an update on the proposed Dachverbandes Osteologie (DVO) guidelines for 2006.

Summary:

  • Secondary osteoporosis arises from non-physiological factors, with glucocorticoid use being a primary cause.
  • While endogenous Cushing syndrome infrequently impacts bone density, glucocorticoid therapy for inflammatory conditions significantly increases osteoporosis risk.

Related Experiment Videos

Last Updated: Jul 16, 2026

Tension-Free Weight-Bearing Model of Steroid-Induced Osteonecrosis of Femoral Head in Rats
05:55

Tension-Free Weight-Bearing Model of Steroid-Induced Osteonecrosis of Femoral Head in Rats

Published on: September 27, 2024

  • The article reviews existing data and updates management guidelines for glucocorticoid-induced osteoporosis.

    • Impact:

    • Informs clinicians about the prevalence and causes of secondary osteoporosis.
    • Provides updated guidelines for managing glucocorticoid-induced osteoporosis.
    • Aims to improve patient outcomes by optimizing osteoporosis treatment in patients on glucocorticoids.