Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 24, 2026

Using Saccadometry with Deep Brain Stimulation to Study Normal and Pathological Brain Function

Using Saccadometry with Deep Brain Stimulation to Study Normal and Pathological Brain Function

Published on: July 14, 2016

Spatio-temporal brain dynamics underlying saccade execution, suppression, and error-related feedback.

Anthony T Herdman¹, Jennifer D Ryan

¹Rotman Research Institute, Baycrest, Toronto, ON, Canada.

Journal of Cognitive Neuroscience

|March 6, 2007

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Where we look, what we know: how hippocampal predictions shape, and are shaped by, eye movements.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026

Same author

Brain Structures and Cognitive Decline: Moderation Analysis of the PACt-MD Randomized Clinical Trial of Brain Stimulation Plus Cognitive Remediation in Older Adults With Remitted Depression or Mild Cognitive Impairment.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry·2026

Same author

The Canadian multi-ethnic research on aging (CAMERA) study: Design, participant characteristics, and preliminary findings.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

Same author

Novelty Discrimination of Configural Objects in the Perirhinal and Anterolateral Entorhinal Cortices Is Impacted by Aging.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026

Same author

Phase-Locking Saccades to Posterior Alpha Oscillations Improves the Neural Representation of Visual Objects during Memory Formation.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026

Same author

The Feasibility and Acceptability of a Remotely Delivered, Combined Exercise Intervention on Cognitive Function in Patients With Breast Cancer Following Chemotherapy: Randomized Controlled Trial.

JMIR cancer·2026

This study reveals the precise timing of brain region activation during goal-directed saccades and error correction. Frontal eye fields and visual cortex activity predict saccade success and guide error feedback for improved eye movements.

Area of Science:

Neuroscience
Cognitive Science
Ophthalmology

Background:

Saccadic eye movements are crucial for visual exploration and are supported by specific neural regions.
Understanding the temporal dynamics of neural activation during saccade execution and error feedback is essential for cognitive neuroscience.

Purpose of the Study:

To delineate the precise sequence of neural activation during goal-directed saccade execution.
To investigate the temporal dynamics of error-related feedback following saccadic eye movements.
To establish a novel methodology for concurrently recording behavioral and neural data during complex cognitive tasks.

Main Methods:

Simultaneous recording of behavioral responses (eye movements) and neural activity (magnetoencephalography - MEG).

More Related Videos

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity

Published on: March 18, 2019

An Emerging Target Paradigm to Evoke Fast Visuomotor Responses on Human Upper Limb Muscles

An Emerging Target Paradigm to Evoke Fast Visuomotor Responses on Human Upper Limb Muscles

Published on: August 25, 2020

Related Experiment Videos

Last Updated: Jun 24, 2026

Using Saccadometry with Deep Brain Stimulation to Study Normal and Pathological Brain Function

Using Saccadometry with Deep Brain Stimulation to Study Normal and Pathological Brain Function

Published on: July 14, 2016

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity

Published on: March 18, 2019

An Emerging Target Paradigm to Evoke Fast Visuomotor Responses on Human Upper Limb Muscles

An Emerging Target Paradigm to Evoke Fast Visuomotor Responses on Human Upper Limb Muscles

Published on: August 25, 2020

Participants performed an antisaccade task to elicit goal-directed and reflexive saccades.

Analysis of neural responses in relation to saccade onset and behavioral outcomes.

Main Results:

Frontal eye field (FEF) and visual cortex activity preceded saccade execution, differentiating goal-directed from reflexive saccades.
Post-saccade activity in these regions distinguished correct from incorrect saccades.
Error-related activity in the FEF preceded visual regions, suggesting a feedback loop for corrective eye movements.

Conclusions:

This study provides the first empirical evidence of simultaneous remote eye-tracking and MEG recording.
The findings demonstrate a novel converging evidence approach using coupled behavioral and neuroimaging technologies.
This methodology offers a powerful tool for elucidating the neural underpinnings of dynamic cognitive processes like saccade control and error correction.