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Updated: Jul 16, 2026
06:46
Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
ACG practice guidelines: esophageal reflux testing
1Division of Gastroenterology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611-2951, USA.
The American Journal of Gastroenterology
|March 6, 2007
Summary
Objective tests for esophageal reflux are crucial for managing gastroesophageal reflux disease, especially for patients with endoscopy-negative reflux or refractory symptoms. This review assesses traditional and new methods for accurate reflux diagnosis.
Area of Science:
- Gastroenterology
- Digestive Physiology
Background:
- Gastroesophageal reflux disease (GERD) management has advanced, yet challenges remain for specific patient groups.
- Patients with endoscopy-negative reflux disease (ENRD) and those refractory to proton pump inhibitor (PPI) therapy require objective reflux assessment.
Purpose of the Study:
- To review and assess current and emerging diagnostic techniques for esophageal reflux.
- To provide recommendations for the clinical application of esophageal reflux testing.
Main Methods:
- Discussion of conventional catheter-based pH monitoring and its interpretation.
- Review of symptom-reflux association analyses and limitations.
- Assessment of novel techniques including wireless pH capsule monitoring and esophageal impedance testing.
Main Results:
- Conventional pH monitoring remains a key tool, with improved interpretation methods.
- Newer techniques like impedance testing offer complementary data for reflux assessment.
- Understanding limitations and clinical utility across different esophageal and gastric locations is crucial.
Conclusions:
- Objective esophageal reflux testing is essential for optimizing GERD management.
- A range of diagnostic tools, from traditional pH monitoring to impedance and wireless capsules, are available.
- Guidelines and recommendations aid in selecting appropriate tests for individual patient needs.
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