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Related Experiment Videos

Schistosomiasis and pregnancy.

Jennifer F Friedman1, Priya Mital, Hemal K Kanzaria

  • 1Center for International Health Research, Rhode Island Hospital, 55 Claverick Street, Providence, RI 02903, USA. jennifer_friedman@brown.edu

Trends in Parasitology
|March 6, 2007
PubMed
Summary

Schistosomiasis infection in pregnant women may negatively impact maternal and infant health. More research is needed to understand these effects and the safety of praziquantel treatment during pregnancy.

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Area of Science:

  • Neglected tropical diseases
  • Maternal and child health
  • Parasitology

Background:

  • Schistosomiasis affects millions of women of childbearing age globally.
  • Limited data exists on schistosome-associated morbidity in pregnant women and their offspring.
  • Animal models suggest adverse effects of schistosome infection on pregnancy outcomes.

Purpose of the Study:

  • To highlight the critical need for research on schistosome infection's impact on pregnancy.
  • To emphasize the importance of well-designed studies for improving birth outcomes in endemic regions.
  • To address the safety of praziquantel treatment in pregnant women.

Main Methods:

  • Review of existing literature, including case reports and observational studies.
  • Analysis of animal model data on schistosome infection and pregnancy.

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  • Identification of research gaps in maternal schistosome infection and treatment.

    • Main Results:

    • Maternal schistosome infection is associated with poor birth outcomes.
    • Evidence suggests a link between maternal infection and decreased birth weight.
    • Data on fetal and neonatal outcomes remains scarce.

    Conclusions:

    • Further rigorous research is essential to quantify the impact of schistosomiasis on pregnancy.
    • Investigating praziquantel's safety in pregnancy is crucial for treatment guidelines.
    • Improving birth outcomes in schistosomiasis-endemic areas requires targeted interventions and research.