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Successful treatment of a bowel perforation after chemotherapy for Burkitt lymphoma

Stephanie R Goldberg1, Kamar Godder, David A Lanning

  • 1Department of Surgery/Division of Pediatric Surgery, Medical College of Virginia Hospitals/Virginia Commonwealth University, Richmond, VA 23298, USA.

Journal of Pediatric Surgery
|March 6, 2007
PubMed

Insights

Chemotherapy can cause intestinal perforation in children with Burkitt lymphoma. This case report details the successful survival and care of a pediatric patient experiencing jejunal perforation, highlighting a lack of existing guidelines.

Area of Science:

  • Pediatric Oncology
  • Gastrointestinal Surgery

Background:

  • Chemotherapy-induced intestinal perforation is a rare but serious complication in Burkitt lymphoma treatment.
  • Existing pediatric literature lacks detailed reports and survival data for this specific complication.

Observation:

  • A 5-year-old boy developed jejunal perforation during Burkitt lymphoma treatment.
  • His case is unique as there are no prior reports of pediatric survival from chemotherapy-induced perforation.

Findings:

  • The patient survived jejunal perforation, indicating potential for recovery.
  • Critical care aspects contributing to survival were identified.

Implications:

  • This case underscores the need for diagnostic and treatment guidelines for chemotherapy-induced intestinal perforation in pediatric Burkitt lymphoma.
  • Further research is needed to establish protocols for managing this complication and guiding chemotherapy continuation.

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