Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Proprioception and myoclonus.

C Rossi-Durand1

  • 1Laboratoire de physiologie et physiopathologie de la motricité (P3M), CNRS-UMR 6196 CNRS/université de la Méditerranée, 31, chemin Joseph-Aiguier, 13402 Marseille cedex 20, France. crd@dpm.cnrs-mrs.fr

Neurophysiologie Clinique = Clinical Neurophysiology
|March 6, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Increased muscle spindle sensitivity to movement during reinforcement manoeuvres in relaxed human subjects.

The Journal of physiology·2000
Same author

Comparison of the depression of H-reflexes following previous activation in upper and lower limb muscles in human subjects.

Experimental brain research·1999
Same author

Muscle spindle activity following muscle tendon vibration in man.

Neuroscience letters·1999
Same author

Task-dependence of muscle afferent monosynaptic inputs to human extensor carpi radialis motoneurones.

Electroencephalography and clinical neurophysiology·1997
Same author

Peripheral proprioceptive modulation in crayfish walking leg by serotonin.

Brain research·1993
Same author

Serotonin and proctolin modulate the response of a stretch receptor in crayfish.

Brain research·1991
Same journal

Neurophysiological mechanisms of extracorporeal shock wave therapy in post-stroke spasticity.

Neurophysiologie clinique = Clinical neurophysiology·2026
Same journal

Reduced electroencephalogram power and no change in peak alpha frequency in individuals with chronic migraine: a cross-sectional investigation.

Neurophysiologie clinique = Clinical neurophysiology·2026
Same journal

Reading the palm with MScanFit MUNE in spinal muscular atrophy and Hirayama disease: a pilot study.

Neurophysiologie clinique = Clinical neurophysiology·2026
Same journal

Effects of non-invasive brain stimulation on gait and corticospinal plasticity in children and adolescents with cerebral palsy: A systematic review.

Neurophysiologie clinique = Clinical neurophysiology·2026
Same journal

Cortical connectivity abnormalities assessed by TMS-EEG in patients after a transient ischemic attack.

Neurophysiologie clinique = Clinical neurophysiology·2026
Same journal

Anterior cingulate activity is associated with autonomic reactivity to experimentally induced pain.

Neurophysiologie clinique = Clinical neurophysiology·2026
See all related articles

Muscle spindles provide crucial sensory information for proprioception and motor control. Understanding their function and spinal reflexes is key to diagnosing neurological disorders like myoclonus.

Area of Science:

  • Neuroscience
  • Motor Control
  • Sensory Physiology

Background:

  • Muscle spindles are mechanoreceptors vital for proprioception and motor control.
  • Fusimotor command (gamma-motoneurons) regulates spindle sensitivity during motor actions.
  • Dysfunction in the fusimotor system may link to clinical signs like sensorimotor cortex hyperexcitability in myoclonus.

Purpose of the Study:

  • To review the structural and functional properties of muscle spindles and their role in motor control.
  • To explore the projections of spindle afferents into the spinal cord.
  • To discuss the dysfunction of spinal sensorimotor networks in neurological disorders.

Main Methods:

  • Review of existing literature on muscle spindle structure, function, and neural pathways.

Related Experiment Videos

  • Analysis of the complexity of the monosynaptic reflex.
  • Discussion of clinical methods for testing motoneuron and spinal network excitability.

    • Main Results:

    • Muscle spindles, regulated by fusimotor neurons, are essential for precise motor control.
    • Spindle afferent projections and spinal sensorimotor networks are complex.
    • The monosynaptic reflex, though simple in organization, is crucial for assessing spinal excitability.

    Conclusions:

    • Understanding muscle spindle function and spinal reflex mechanisms is critical for interpreting neurological changes.
    • Factors like pre-synaptic inhibition and post-activation depression influence reflex amplitude.
    • Accurate interpretation of spinal excitability requires knowledge of normal reflex function in neurological conditions.