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Published on: May 7, 2018
Methyl spongoate, a cytotoxic steroid from the Sanya soft coral Spongodes sp
Xiao-Hong Yan1, Li-Ping Lin, Jian Ding
1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.
Bioorganic & Medicinal Chemistry Letters
|March 6, 2007
Abstract:
A new steroid with an uncommon 21-oic acid methyl ester moiety designated methyl spongoate (1) which exhibited potent cytotoxicity against BEL-7402 tumor cells in vitro has been isolated from the Sanya soft coral Spongodes sp. Its structure was determined by detailed interpretation of spectroscopic data and by comparison with related compounds.
