Related Experiment Video
Updated: Jul 16, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
Published on: May 31, 2016
[Osteoporosis and atherosclerosis]
Yasushi Omura1, Yoshihiko Nishio, Atsunori Kashiwagi
1Shiga University of Medical Science, Department of Medicine, Division of Endocrinology and Metabolism.
Abstract:
Many epidemiological studies have shown an association between osteoporosis and vascular calcification or atherosclerotic diseases (coronary heart disease, stroke, peripheral vascular disease) in the elderly or postmenopausal women. These results indicate that osteoporosis and atherosclerosis might be linked by common risk factors or pathological mechanisms. Dyslipidemia has the correlation to both osteoporosis and atherosclerosis. Statins, nitorogen-containing bisphosphonates, and estrogens have the favorable effects on lipid profiles as well as vasculature, or bone mineral density. Thus, these therapeutic approaches might have dual effects on bone and vasculature.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Atherosclerosis I: Introduction
Coronary Artery Disease I: Introduction
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
Hypertension II: Pathophysiology
Coronary Artery Disease II: Pathophysiology