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Updated: Jul 16, 2026

Applications of Liquid-Chromatography Tandem Mass Spectrometry in Natural Products Research: Tropane Alkaloids as a Case Study
Published on: March 8, 2024
Alkaloids of Androcymbium melanthioides var. stricta1
H Potesilová1, P Sedmera, D Guénard
1Institute of Medical Chemistry, Medical Faculty, Palacký University, S. Allende 3, 77515 Olomouc, CSSR.
Abstract:
The aerial parts of ANDROCYMBIUM MELANTHIOIDES yielded known alkaloids cornigerine, colchicine, N-formyl- N-deacetylcolchicine, 2-demethylcolchicine, 3-demethylcolchicine, demecolcine, 2-demethyldemecolcine, 3-demethyldemecolcine, beta-lumicornigerine, beta-lumicolchicine, gamma-lumicolchicine, androcymbine, O-methylandrocymbine, and melanthioidine. Of these, O-methylandrocymbine and beta-lumicornigerine are reported for the first, time. The alkaloid, formerly designated as compound AM-3, has been identified as N-deacetyl- N-dimethyl-gamma-lumicornigerine 1. Its spectral data are given.
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