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Updated: Jul 16, 2026

Measurement of Myocardial Lactate Production for Diagnosis of Coronary Microvascular Spasm
06:18

Measurement of Myocardial Lactate Production for Diagnosis of Coronary Microvascular Spasm

Published on: September 17, 2021

[Lactic acid dehydrogenase in the diagnosis of rheumatic carditis]

G Caldara1

  • 1Ospedale di Circolo di Cantù.

Archivio Per Le Scienze Mediche
|September 1, 1969
PubMed

Insights

Lactic acid dehydrogenase (LDH) levels are normal in inactive rheumatic heart disease and non-rheumatic heart failure. Elevated LDH is a valuable indicator for diagnosing active rheumatic carditis, surpassing SGOT in utility.

Area of Science:

  • Biochemistry
  • Cardiology
  • Diagnostic Medicine

Context:

  • Rheumatic carditis diagnosis
  • Isoenzyme analysis
  • Biomarker utility

Purpose:

  • Evaluate lactic acid dehydrogenase (LDH) and isoenzymes for diagnosing active rheumatic carditis.
  • Compare diagnostic utility of LDH versus serum glutamic-oxaloacetic transaminase (SGOT).

Summary:

  • LDH levels remain normal in inactive chronic rheumatic valvulopathy and non-rheumatic cardiac insufficiency.
  • Elevated LDH demonstrates significantly greater diagnostic value than SGOT in active rheumatic carditis.

Impact:

  • Highlights LDH as a key biomarker for active rheumatic carditis.
  • Informs diagnostic strategies for rheumatic heart disease.

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