[The embryology and pathogenesis of congenital anophthalmus]

The picture presented by congenital anophthalmus is presented and its primary, secondary and degenerative forms are distinguished. The frequency of this rare abnormality is discussed with reference to the literature data, both clinical and experimental, and the possible part played by various physical, chemical, infectious and genetic factors is explained. Some considerations are expressed concerning the qualitative and chronological mechanisms of action and the harmful factors responsible for this embryopathy.