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[Occupational allergies to bromelain].

V van Kampen1, R Merget, T Brüning

  • 1Berufsgenossenschaftliches Forschungsinstitut für Arbeitsmedizin. kampen@bgfa.de

Pneumologie (Stuttgart, Germany)
|March 8, 2007
PubMed
Summary
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Occupational exposure to bromelain, an enzyme from pineapple, can cause specific airway sensitization. Evidence from multiple studies indicates an immunological mechanism behind these allergic reactions in workers.

Area of Science:

  • Enzymology
  • Occupational Health
  • Immunology

Context:

  • Bromelain, a protease derived from pineapple (Ananas comosus), is widely used in various industries.
  • Occupational exposure to enzyme dusts, including bromelain, is a known risk factor for allergic diseases.
  • Previous literature suggests a link between enzyme exposure and respiratory issues.

Purpose:

  • To review and evaluate existing literature on occupational airway sensitization specifically caused by bromelain.
  • To consolidate evidence regarding the immunological basis of bromelain-induced respiratory allergies.
  • To assess the consistency of findings across different diagnostic methods.

Summary:

  • Multiple studies demonstrate clear cases of specific airway sensitization due to occupational bromelain exposure.

Related Experiment Videos

  • Consistent findings include characteristic symptoms, positive skin prick tests, and detection of specific IgE antibodies.
  • Specific bronchoprovocation tests further support the diagnosis and suggest an underlying immunological mechanism.
  • Impact:

    • Highlights the occupational health risks associated with bromelain enzyme exposure in industrial settings.
    • Provides a consolidated review for healthcare professionals and safety managers to understand bromelain allergy.
    • Emphasizes the need for appropriate protective measures to prevent occupational airway sensitization to bromelain.