Related Experiment Video
Updated: Jul 16, 2026
09:58
A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice
Published on: April 13, 2010
[Measuring airway inflammation in clinical practise - application and interpretation]
1Die Institutsangaben sind am Ende des Beitrags gelistet. o.holz@pulmoresearch.de
Pneumologie (Stuttgart, Germany)
|March 8, 2007
Summary
Measuring exhaled nitric oxide (FeNO) offers a cost-effective, non-invasive method for detecting eosinophilic airway inflammation, benefiting asthma and COPD patient diagnosis and management.
Area of Science:
- Pulmonary Medicine
- Allergy and Immunology
Context:
- Airway inflammation is central to asthma and COPD pathogenesis.
- Corticosteroids are primary treatments, yet inflammation is underutilized in routine care.
- Eosinophilic airway inflammation is a key target, responding well to corticosteroids.
Purpose:
- To review the basics, technical aspects, clinical value, and interpretation of fractional exhaled nitric oxide (FeNO) measurements.
- To highlight FeNO as an economic alternative to induced sputum for detecting eosinophilic airway inflammation.
- To guide clinicians in utilizing FeNO for improved diagnosis and disease management.
Summary:
- Fractional exhaled nitric oxide (FeNO) measurement is a viable, non-invasive tool for assessing eosinophilic airway inflammation.
- FeNO correlates with sputum eosinophils, offering a more practical alternative for outpatient settings.
- Recent advancements in handheld analyzers facilitate rapid FeNO analysis, even in pediatric populations.
Impact:
- Facilitates earlier and more accurate diagnosis of inflammatory airway diseases.
- Enables personalized treatment strategies, optimizing corticosteroid therapy.
- Improves patient outcomes by guiding effective disease management in asthma and COPD.
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