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Updated: Jul 16, 2026

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
Comparative study of optical sources in the near infrared for optical coherence tomography applications
Lionel Carrion1, Michel Lestrade, Zhiqiang Xu
1Ecole Polytechnique de Montréal, Department of Engineering Physics, Optoelectronics Laboratory, P.O. Box 6079, Station Centre-ville, Montréal, Québec H3C 3A7 Canada. lionel.carrion@polymtl.ca
Abstract:
Optical coherence tomography (OCT) is a powerful, noninvasive biomedical technique that uses low-coherence light sources to obtain in-depth scans of biological tissues. We report results obtained with three different sources emitting at 1570, 1330, and 810 nm, respectively. Attenuation and backscattering measurements are obtained with these sources for several in vitro biological tissues. From these measurements, we use a graphical method to make comparisons of the penetration depth and backscattering intensity of each wavelength for the studied samples. The influence of the coherence length of each source is also taken into account in order to make a more relevant comparison.
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