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Frequency tracking in optical Doppler tomography using an adaptive notch filter.

Yueli Chen¹, Peter Willett, Quing Zhu

¹University of Connecticut, Electrical and Computer Engineering Department, Storrs, Connecticut 06269, USA.

Journal of Biomedical Optics

|March 9, 2007

Summary

We developed a new adaptive notch filter (ANF) for Optical Doppler Tomography (ODT) to accurately track blood flow in tissues. This efficient time-domain method improves noise robustness and estimation accuracy for real-time imaging.

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Doppler Optical Coherence Tomography of Retinal Circulation

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Published on: September 18, 2012

Area of Science:

Biomedical Optics
Medical Imaging Technology
Translational Medicine

Background:

Optical Doppler Tomography (ODT) extends Optical Coherence Tomography (OCT) for subsurface blood flow analysis in biological tissues.
Accurate Doppler frequency estimation is crucial for ODT's diagnostic capabilities.
Existing methods often require Fourier transformation and may lack computational efficiency for real-time applications.

Purpose of the Study:

To introduce a novel, computationally efficient frequency estimation technique for ODT.
To develop a minimal-parameter adaptive notch filter (ANF) for tracking depth-resolved Doppler frequencies.
To evaluate the performance of the ANF in terms of noise robustness and estimation accuracy.

Main Methods:

Implementation of an adaptive notch filter (ANF) operating in the time domain.
Avoidance of Fourier transformation for enhanced computational efficiency.
Simulation and experimental imaging using the proposed ANF technique.

Main Results:

The ANF successfully tracks depth-resolved Doppler frequencies in biological tissues.
The proposed technique demonstrates superior noise robustness compared to existing algorithms.
High estimation accuracy was achieved, validated through simulations and imaging results.
The time-domain approach offers significant computational efficiency for real-time ODT.

Conclusions:

The novel ANF provides an efficient and accurate method for Doppler frequency estimation in ODT.
This technique is well-suited for real-time implementation in ODT systems.
The ANF enhances the functional capabilities of ODT for studying subsurface blood flow.