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[Fever--friend or foe?].

K Kouvalainen1

  • 1Pediatriska kliniken, Uleåborgs universitet, Uleåborg.

Nordisk Medicin
|January 1, 1992
PubMed
Summary

Fever can aid the body's defense against microbes, but it also poses risks. Antipyretics (fever-reducing drugs) should be used cautiously when fever causes harm or distress.

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Area of Science:

  • Immunology
  • Physiology
  • Pharmacology

Background:

  • Extensive research since 2000 investigates fever's role in host defense against pathogens.
  • Evidence suggests fever can be beneficial in certain circumstances.
  • However, fever can also lead to adverse effects and complications.

Purpose of the Study:

  • To review the dual role of fever in the context of host defense.
  • To discuss the risks and benefits associated with fever.
  • To provide guidance on the appropriate use of antipyretics.

Main Methods:

  • Literature review of studies on fever and host defense.
  • Analysis of evidence regarding the beneficial and detrimental effects of fever.
  • Examination of clinical guidelines for antipyretic use.

Main Results:

  • Fever demonstrates a complex role, offering benefits in combating microbial infections.
  • Significant risks and negative consequences can arise from elevated body temperature.
  • The decision to use antipyretics requires careful consideration of the patient's condition.

Conclusions:

  • Fever is a double-edged sword in host defense, with both advantages and disadvantages.
  • Judicious use of antipyretics is crucial, particularly when fever poses a hazard or causes significant discomfort.
  • Further research is needed to fully elucidate the mechanisms and optimal management of fever.

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