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Coffee intake and incidence of hypertension
Cuno S P M Uiterwaal1, W M Monique Verschuren, H Bas Bueno-de-Mesquita
1Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, Netherlands. c.s.p.m.uiterwaal@umcutrecht.nl
Insights
Coffee abstinence is linked to reduced hypertension risk compared to low consumption. Women showed an inverse U-shaped relationship between coffee intake and hypertension incidence, suggesting moderate intake may be beneficial.
Area of Science:
- Cardiovascular Health
- Epidemiology
- Nutritional Science
Background:
- Limited long-term longitudinal data exists on the relationship between coffee consumption and hypertension.
- Understanding this association is crucial for public health recommendations.
Purpose of the Study:
- To investigate the association between coffee intake and the incidence of hypertension.
- To explore potential dose-response relationships and gender-specific effects.
Main Methods:
- A cohort study of 6368 participants (2985 men, 3383 women) with 6 and 11-year follow-ups.
- Coffee intake was assessed via questionnaires and categorized.
- Hypertension defined by blood pressure thresholds or antihypertensive medication use.
Main Results:
- Coffee abstainers had a significantly lower risk of hypertension compared to low consumers (>0-3 cups/day).
- Women consuming >6 cups/day showed a reduced risk compared to those drinking >0-3 cups/day.
- Older participants (≥39 years) at baseline exhibited lower systolic blood pressure per cup of coffee intake daily.
Conclusions:
- Coffee abstinence is associated with a lower risk of developing hypertension.
- An inverse U-shaped relationship between coffee intake and hypertension risk was observed in women.
- Findings suggest potential benefits of coffee consumption, particularly in women, warranting further investigation.
Background:
The long-term longitudinal evidence for a relation between coffee intake and hypertension is relatively scarce.
Objective:
The objective was to assess whether coffee intake is associated with the incidence of hypertension.
Design:
This study was conducted on a cohort of 2985 men and 3383 women who had a baseline visit and follow-up visits after 6 and 11 y. Baseline coffee intake was ascertained with questionnaires and categorized into 0, >0-3, >3-6, and >6 cups/d. Hypertension was defined as a mean systolic blood pressure (SBP) >or=140 mm Hg over both follow-up measurements, a mean diastolic blood pressure (DBP) >or=90 mm Hg over both follow-up measurements, or the use of antihypertensive medication at any follow-up measurement.
Results:
Coffee abstainers at baseline had a lower risk of hypertension than did those with a coffee intake of >0-3 cups/d [odds ratio (OR): 0.54; 95% CI: 0.31, 0.92]. Women who drank >6 cups/d had a lower risk than did women who drank >0-3 cups/d (OR: 0.67; 95% CI: 0.46, 0.98). Subjects aged >or=39 y at baseline had 0.35 mm Hg (95% CI: -0.59, -0.11 mm Hg) lower SBP per cup intake/d and 0.11 mm Hg lower DBP (95% CI: -0.26, 0.03 mm Hg) than did those aged <39 y at baseline, although the difference in DBP was not statistically significant.
Conclusions:
Coffee abstinence is associated with a lower hypertension risk than is low coffee consumption. An inverse U-shaped relation between coffee intake and risk of hypertension was observed in the women.
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