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5, 6, 4'-Trihydroxy-7, 3'-dimethoxyflavone and other Methoxylated Flavonoids Isolated from Thymus satureiodes

B Voirin1, M R Viricel, J Favre-Bonvin

  • 1Laboratoire de Phytochimie, U. E. R. des Sciences de la Nature, Université Claude Bernard Lyon-1, 43 Boulevard du 11 novembre 1918, F-69622 Villeurbanne Cédex, France.

Planta Medica
|December 1, 1985
PubMed

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Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase01:11

Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase

Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...