Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Toxic anterior segment syndrome].

M Filip1, Carmen Dragne, A Filip

  • 1Clinica de Oftalmologie Amaoptimex, Bucureşti. MIRCEAFILIP@AMAOPTIMEX.RO

Oftalmologia (Bucharest, Romania : 1990)
|March 10, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

COVID-19 vaccine acceptance among medical students in Romania.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society·2022
Same author

Comparison of magnetic resonance angiography techniques to brain digital subtraction arteriography in the setting of mechanical thrombectomy: A non-inferiority study.

Revue neurologique·2022
Same author

The impact of 3,4-methylendioxymetamphetamine (MDMA) abstinence on seeking behavior and the expression of the D<sub>2</sub>-like and mGlu<sub>5</sub> receptors in the rat brain using saturation binding analyses.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society·2020
Same author

The effect of myo-inositol, vitamin D3 and melatonin on the oocyte quality and pregnancy in in vitro fertilization: a randomized prospective controlled trial.

European review for medical and pharmacological sciences·2020
Same author

[Minimally Invasive Posterior Lumbar Interbody Fusion and Instrumentation - Outcomes at 24-Month Follow-up].

Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca·2020
Same author

Daily oral administration of chlorogenic acid prevents the experimental carrageenan-induced oxidative stress.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society·2020
Same journal

[Macular serpiginous choroiditis complicated by macular hole].

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

[Therapeutic approach in persistent diabetic macular edema].

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

[Preliminary results of treatment with aflibercept].

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

MANAGEMENT OF DIABETIC RETINOPATHY, PREVALENCE AND CLINICAL CLASSIFICATION.

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

[Changes in intraocular pressure depending on posture].

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

[Treatment for penetrating wound caused by metallic intraocular foreign body].

Oftalmologia (Bucharest, Romania : 1990)·2015
See all related articles

Two cases of Toxic Anterior Segment Syndrome (TASS) occurred after cefuroxime was administered into the anterior chamber during eye surgery. Researchers decided to stop using cefuroxime due to these TASS events.

Area of Science:

  • Ophthalmology
  • Surgical Complications
  • Pharmacology

Background:

  • Current ESCRS guidelines recommend intracameral cephalosporin injection post-surgery to prevent endophthalmitis.
  • Cefuroxime is a commonly used cephalosporin for intraocular administration.

Observation:

  • Two patients developed Toxic Anterior Segment Syndrome (TASS) following anterior chamber administration of cefuroxime (Axetin).
  • The TASS events occurred despite the prophylactic intention of the antibiotic injection.

Findings:

  • Intracameral cefuroxime administration was associated with TASS in these cases.
  • Diagnosis and management elements of TASS were observed and discussed.

Implications:

  • The findings suggest a potential risk of TASS with intracameral cefuroxime.

Related Experiment Videos

  • Discontinuation of cefuroxime for intraocular prophylaxis may be warranted in certain clinical settings.
  • Further investigation into the safety profile of intracameral antibiotics is recommended.