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Updated: Jul 16, 2026

Ultrasonographic Evaluation of Salivary Glands for Sjogren's Syndrome: Diagnostic and Monitoring Insights
Published on: October 13, 2023
[Lacrimal proteins electrophoretic analysis--diagnostic method in secondary Sjogren syndrome]
Viorica Mădălina Cojocaru1, Coziana Ciurtin, Elena Puchianu
1Spitalul Clinic de Urgenţe Oftalmologice, Bucureşti.
Purpose:
We analysed and compared electrophoretic tear protein patterns of healthy subjects and patients with different autoimmune diseases associated with secondary Sjogren's syndrome.
Materials And Methods:
Tears were collected using the Schirmer's method. Proteins were separated by sodium-dodecyl sulfate poliacrylamide gel electrophoresis. The lanes were stained by Coomassie blue and/or silver.
Results:
Lactoferrin, albumin, lipocalin and lysozyme were found to be the main components being identified using molecular weight markers.
Conclusions:
Electrophoretic analysis of tear proteins patterns is a fast, reproducible and simple method which provides information about the possibility of lacrimal gland involvement in autoimmmune diseases.
