Related Experiment Video
Updated: Aug 10, 2026

07:28
Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
Published on: July 10, 2018
Perioral dermabrasion: clinical and experimental studies
1Lidingö-Kliniken, Sweden.
Aesthetic Plastic Surgery
|January 1, 1992
Summary
Dermabrasion effectively treats perioral wrinkles for over three years using wire brush or diamond fraise tools. While slight bleaching and milia can occur, dermabrasion offers an advantage over chemical peels by avoiding severe depigmentation.
Area of Science:
- Dermatology
- Plastic Surgery
Background:
- Wrinkles around the lips and chin are common cosmetic concerns.
- Dermabrasion is a procedure used to improve skin texture and appearance.
Purpose of the Study:
- To evaluate the efficacy and side effects of dermabrasion for perioral wrinkles.
- To compare different dermabrading tools, anesthesia adjuncts, and dressings.
Main Methods:
- 54 patients with perioral wrinkles underwent dermabrasion using wire brush or diamond fraise.
- Histological examination compared the abraded surfaces.
- EMLA cream's efficacy as an anesthetic adjunct was assessed.
- Five types of dressings were compared for epithelialization and comfort.
Main Results:
- Significant improvement in wrinkles lasting over three years was achieved with both tools.
- Permanent, slight bleaching occurred in 66% of patients; milia in <20%.
- Diamond fraise produced a smoother surface than the wire brush.
- EMLA cream reduced local anesthetic requirements but was insufficient alone for perioral anesthesia.
- Vigilon was identified as the most suitable dressing.
Conclusions:
- Dermabrasion is a durable and effective treatment for perioral wrinkles.
- Tool selection (diamond fraise preferred for smoothness) and appropriate dressings (Vigilon) are important.
- EMLA cream can be a useful adjunct to local anesthesia in this region.
- Dermabrasion avoids the severe depigmentation associated with chemical peels.

