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Updated: Jul 16, 2026

State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Quality control of an image-scoring method for nuchal translucency ultrasonography
Nicolas Fries1, Marc Althuser, Marianne Fontanges
1Collège Français d'Echographie Foetale, Paris, France. fries@cfef.org
Objective:
The objective of the study was to describe a new image-scoring method (NISM) for the measurement of nuchal translucency and crown-rump length on ultrasound scans and to establish interreviewer reliability.
Study Design:
This NISM was based on 8 criteria on a scale of 4 levels (1-4) established on clearly defined ultrasound reference marks. Ten reviewers assessed the same images of 30 fetuses. After a short training period, the same images and those of 30 new fetuses were scored by these 10 reviewers.
Results:
The differences in scores among the 10 reviewers were significant for 4 of 45 pairwise comparisons before training, but no pairwise comparison was significant after training. Interreviewer variance was significantly lower after training (P = .045). The intraclass correlations before and after training were 0.75 and 0.82. For each criterion, the scores were dichotomized into 2 categories (1-2 vs 3-4). Kappa values for each criterion were substantial (0.61 to 0.80) or even almost perfect (0.81 to 1.00).
Conclusion:
This NISM was highly reliable for the total scores and for each criterion evaluating the image of nuchal translucency and crown-rump length and provides a relevant quality control tool for ultrasound operators.
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