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Updated: Jul 16, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
Published on: September 12, 2011
Offering to share: how to put heads together in autism neuroimaging
Matthew K Belmonte1, John C Mazziotta, Nancy J Minshew
1Department of Human Development, Cornell University, Martha Van Rensselaer Hall, Ithaca, NY 14853-4401, USA. belmonte@mit.edu
Abstract:
Data sharing in autism neuroimaging presents scientific, technical, and social obstacles. We outline the desiderata for a data-sharing scheme that combines imaging with other measures of phenotype and with genetics, defines requirements for comparability of derived data and recommendations for raw data, outlines a core protocol including multispectral structural and diffusion-tensor imaging and optional extensions, provides for the collection of prospective, confound-free normative data, and extends sharing and collaborative development not only to data but to the analytical tools and methods applied to these data. A theme in these requirements is the need to preserve creative approaches and risk-taking within individual laboratories at the same time as common standards are provided for these laboratories to build on.
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