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Updated: Jul 16, 2026

Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants
Published on: August 5, 2021
[Preparation and structural detection of antibacterial hydroxyapatite coating material on Ti implant]
Zi-Yuan Zhu1, Fu-Qiang Zhang, Xue-Bin Zheng
1Department of Prosthodontics, College of Stomatology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Research Institute of Stomatology, Shanghai 200011, China. yuan1588@sina.com
Purpose:
To investigate the method for preparing antibacterial hydroxyapatite coating material on Ti implant,and detect its surface feature, chemical composition and the crystal structure.
Methods:
The antibacterial hydroxyapatite coating material which contained silver-zirconium phosphate antimicrobial was prepared on the Ti implant by using vacuum plasma spraying technology. Samples were divided into 4 groups according to weight percent of the antimicrobial: group A (0), group B (2%), group C (5%) and group D (10%). The surface feature of each sample was observed under scanning electric microscope. The chemical composition and the crystal structure was detected by electronic probe and X-ray diffraction method respectively.
Results:
The surface feature of each sample showed globular granule with caky structure and air pore. The crystal structure of group A, B, C mainly showed characteristic absorption band of Ca10(OH)2(PO4)6 which degraded while antimicrobial content increased. Except Ca10(OH)2(PO4)6 and CaZr (PO4)2, Na6CaP2O09 also appeared in group D. Ag+ could not be detected by electronic probe in group A and B. The contents of Ag+ in group C and D were similar.
Conclusion:
The antibacterial hydroxyapatite coating material which contained silver can be prepared on the Ti implant by using vacuum plasma spraying technology. The appropriate weight percent of the antimicrobial was 5%.

