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How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children
Published on: August 19, 2020
[Energy expenditure in critically ill children: correlation with clinical characteristics, caloric intake, and
J López-Herce Cid1, C Sánchez Sánchez, S Mencía Bartolomé
1Sección de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, España. pielvi@ya.com
Insights
Energy expenditure (EE) in critically ill children shows wide variability. Indirect calorimetry is a simple, accurate method for measuring EE in these patients, unlike theoretical formulas.
Area of Science:
- Critical care medicine
- Pediatric physiology
- Nutritional support
Context:
- Critically ill infants and children often require precise nutritional management.
- Accurate assessment of energy expenditure (EE) is crucial for optimizing treatment.
- Existing theoretical formulas for predicting EE may not be reliable in this population.
Purpose:
- To investigate energy expenditure (EE) in critically ill pediatric patients.
- To compare measured EE with values predicted by various theoretical formulas.
- To explore correlations between EE and clinical factors, including mechanical ventilation and nutrition.
Summary:
- A prospective study measured EE in 43 critically ill infants and children using indirect calorimetry.
- Measured EE exhibited significant individual variability and was lower in post-cardiac surgery patients.
- Theoretical predictive equations frequently failed to accurately estimate EE, while caloric intake showed some correlation.
Impact:
- Indirect calorimetry provides a simple and potentially generalizable method for accurate EE measurement in critically ill children.
- Findings highlight the limitations of theoretical formulas, emphasizing the need for direct measurement.
- Improved EE assessment can lead to more personalized and effective nutritional strategies in pediatric critical care.
Objective:
To study energy expenditure (EE) in critically ill infants and children and its correlation with clinical characteristics, treatment, nutrition, caloric intake, and predicted energy expenditure calculated through theoretical formulas.
Patients And Methods:
A prospective observational study was conducted in critically ill infants and children. Indirect calorimetry measurements were performed using the calorimetry module of the S5 Datex monitor. Data on mechanical ventilation, nutrition, and caloric intake were registered. Theoretical equations of energy requirement (WHO/FAO, Harris-Benedict, Caldwell-Kennedy, Maffeis, Fleisch, Kleiber and Hunter) were calculated. The statistical analysis was performed using the SPSS 12.0 package.
Results:
Sixty-eight EE determinations were performed in 43 critically ill infants and children aged between 10 days and 15 years old. Measured EE was 58.4 (18.4) kcal/kg/day, with wide individual variability. EE was significantly lower in infants and children who had undergone cardiac surgery than in the remainder. No correlation was found between EE and mechanical ventilation parameters, vasoactive drugs, sedatives, or muscle relaxants. A correlation was found between caloric intake and EE. In a high percentage of patients, predictive equations did not accurately estimate EE. The respiratory quotient was not useful to diagnose overfeeding or underfeeding.
Conclusions:
Wide individual variability in EE was found in critically ill infants and children. Predictive equations did not accurately estimate EE. Indirect calorimetry measured by a specific module is a simple method that could allow generalized use of EE measurement in critically ill pediatric patients undergoing mechanical ventilation.
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