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Updated: Jul 16, 2026

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity
Published on: January 31, 2025
Primary leiomyosarcoma of the innominate vein
Giulio Illuminati1, Fabio Miraldi, Giuseppe Mazzesi
1Francesco Durante Department of Surgery, University of Rome La Sapienza, Rome, Italy. giulio.illuminati@uniroma1.it
Abstract:
Primary venous leiomyosarcoma is rare. We report the case of a primary leiomyosarcoma of the left innominate vein, with neoplastic thrombus extending into the left jugular and subclavian veins. The tumor was curatively resected en bloc with anterior mediastinal and laterocervical lymphatics, through a median sternotomy prolonged into left cervicotomy. Primary venous sarcomas may be associated with prolonged survival in individual cases, with curative resection recommended as the standard treatment, in the absence of distant spread.
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