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Antioxidant activity of Agaricus blazei
O M M F Oliveira1, J C R Vellosa, A S Fernandes
1Unesp, Sao Paulo State University, Biochemistry and Technology Chemistry Department, Instituto de Química, Araraquara-SP, Brazil. olgaenzimologia@yahoo.com.br
Fitoterapia
|March 14, 2007
Summary
The ethanolic extract of Agaricus blazei mushroom, along with its ethyl acetate and hydroalcoholic fractions, demonstrated significant antioxidant activity in this study.
Area of Science:
- Pharmacology
- Mycology
- Natural Product Chemistry
Background:
- Agaricus blazei is a mushroom with a history of traditional use.
- Mushrooms are recognized as a source of bioactive compounds.
- Oxidative stress is implicated in various chronic diseases.
Purpose of the Study:
- To investigate the antioxidant potential of Agaricus blazei extracts and fractions.
- To determine the efficacy of different solvent extraction methods on antioxidant activity.
Main Methods:
- Preparation of ethanolic extract of Agaricus blazei.
- Fractionation of the extract using ethyl acetate and hydroalcoholic solvents.
- Evaluation of antioxidant activity using established in vitro assays (specific assays not detailed in abstract).
Main Results:
- The ethanolic extract of Agaricus blazei exhibited notable antioxidant properties.
- Specific fractions (ethyl acetate and hydroalcoholic) also displayed significant antioxidant capacity.
- Results suggest a concentration-dependent relationship between extract/fraction and antioxidant effect (inferred).
Conclusions:
- Agaricus blazei possesses valuable antioxidant compounds.
- The extraction and fractionation methods employed successfully isolated compounds with antioxidant activity.
- Further research is warranted to identify specific antioxidant compounds and their mechanisms of action.
