Skin care products and subtle data manipulation
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Updated: Jul 16, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
Ronni Wolf1, Edith Orion, Batya Davidovici
1The Dermatology Unit, Kaplan Medical Center, Rechovot, Israel. wolf_r@netvision.net.il
Abstract:
The dermatologists of today need to master the skills to help their patients in choosing skin care products. As physicians and scientists, we are naturally inclined to trust sophisticated and objectively derived data that are published in scientific, peer-reviewed journals and are presented to us in the form of numbers, tables, and graphs. The question that should be asked is whether a product that scored well in sophisticated tests is really superior and more suitable to the needs of our patients? Or, how far can we trust the data in scientific publications? There is no generally accepted methodology for unbiased evaluation of the efficacy and performance of skin care products. There is also no consensus on which test method best reflects the real-life performance of these products. And, most importantly, even the most objective methods and measuring devices can be and often are manipulated to support the claims of superiority of given products. We will show several out of many, many ways of how the study design, protocols, techniques, and end points can legitimately be adapted to the special characteristics of the specific product, emphasizing its advantages.
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