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Published on: September 25, 2009
Ipsilateral parenchymal hemorrhage after hemicraniectomy in a patient suffering from malignant middle cerebral artery
1Technical University Dresden, Neurology Department, Dresden, Germany. claudiadisque@web.de
Introduction:
Early hemicraniectomy reduces mortality in malignant middle cerebral artery (MCA) infarctions to 16%, although the benefit on functional outcome is still unclear. We treat patients with malignant MCA infarction younger than 60 years. Epidural or subgaleal hemorrhages are relatively common complications. Only 1 trial described parenchymal hemorrhage as a complication of hemicraniectomy.
Case Report:
A 55-year-old man was admitted to our stroke unit with right-sided hemiparesis and aphasia. NIHSS was 18; GCS, 3. The initial CT showed hypoattenuation in the basal ganglia and the insular ribbon on the left side. CT-angiography showed M1 occlusion. Despite thrombolysis with rtPA in the 3-hour time window, no recanalization was achieved. We performed early hemicraniectomy. Additionally, we started mild hypothermia and deep sedation to prevent increasing cerebral edema. Control CT on day 2 showed intracerebral hemorrhage and an obstructive hydrocephalus because of intraventricular blood. To avoid herniation, the patient received an extraventricular drainage (EVD). Thereafter, the intracerebral pressure remained stable. The patient was discharged, with a NIHSS of 18 and GCS of 10.
Conclusion:
The reported patient is the first in the literature that suffered from deep hemorrhage after hemicraniectomy. Hemorrhagic transformation might be a risk factor for clinically relevant hemorrhage after hemicraniectomy.
Insights
Early hemicraniectomy for malignant middle cerebral artery infarction can lead to deep hemorrhage, a rare complication. This case highlights hemorrhagic transformation as a potential risk factor following the procedure.
Area of Science:
- Neurosurgery
- Neurology
- Critical Care Medicine
Background:
- Malignant middle cerebral artery (MCA) infarction carries high mortality.
- Early hemicraniectomy significantly reduces mortality but functional outcomes remain debated.
- Hemorrhagic complications, such as epidural or subgaleal hematomas, are known risks of hemicraniectomy.
Observation:
- A 55-year-old male presented with severe stroke symptoms (NIHSS 18, GCS 3) due to left MCA occlusion.
- Despite rtPA and early hemicraniectomy, the patient developed deep intracerebral hemorrhage and obstructive hydrocephalus.
- An extraventricular drainage (EVD) was placed to manage intracranial pressure.
Findings:
- This case represents the first reported instance of deep hemorrhage post-hemicraniectomy in the literature.
- Hemorrhagic transformation of the infarct is identified as a potential risk factor for significant hemorrhage after hemicraniectomy.
- The patient's neurological status remained severe (NIHSS 18, GCS 10) at discharge.
Implications:
- The findings suggest a need for vigilant monitoring for hemorrhagic complications after hemicraniectomy, especially in cases with hemorrhagic transformation.
- Further research is warranted to elucidate the mechanisms and risk factors for deep hemorrhage following this life-saving procedure.
- This case underscores the complex risk-benefit profile of hemicraniectomy in malignant MCA infarction.
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