Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone-fibrin mixture in spinal surgery.

K Ono1, J Shikata, K Shimizu

  • 1Department of Orthopaedic Surgery, Faculty of Medicine, Kyoto University, Japan.

Clinical Orthopaedics and Related Research
|February 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Arrayed silicon prism coupler for a terahertz-wave parametric oscillator.

Applied optics·2008
Same author

Enhancement of terahertz-wave output from LiNbO(3) optical parametric oscillators by cryogenic cooling.

Optics letters·2007
Same author

Bilateral phrenic nerve palsy as a complication of anterior decompression and fusion for cervical ossification of the posterior longitudinal ligament.

Spine·2001
Same author

Lumbar posterolateral fusion with biphasic calcium phosphate ceramic.

Journal of spinal disorders·2001
Same author

Missing anterior cervical plate and screws: a case report.

Spine·2000
Same author

Considerations for surgical treatment of patients with upper lumbar disc herniations.

Journal of spinal disorders·1998
Same journal

Impact Microindentation Evaluates Bone Strength, Bone Quality, and Fracture Susceptibility Across Skeletal Sites: A Cadaver Study.

Clinical orthopaedics and related research·2026
Same journal

What Is the Effect of Robot Reduction in Displaced Pelvic Fractures? A Multicenter Randomized Clinical Trial.

Clinical orthopaedics and related research·2026
Same journal

CORR Insights®: Acute or Delayed TKA for Tibial Plateau Fracture? An Observational Study From the Swedish Arthroplasty Register.

Clinical orthopaedics and related research·2026
Same journal

Reply to the Letter to the Editor: Guest Editorial: Recalling a Recall.

Clinical orthopaedics and related research·2026
Same journal

Radial Head Fractures Cluster in the Anterolateral and Anteromedial Quadrants and Do Not Correlate With Coronoid Fracture Types.

Clinical orthopaedics and related research·2026
Same journal

Reduced Cerebellar Activation With Eyes Closed Is Associated With Delayed Peroneal Reaction Time in Patients With Chronic Ankle Instability.

Clinical orthopaedics and related research·2026
See all related articles

Fibrin sealant mixed with autogeneic bone fragments prevents spinal cord compression from graft instability. This effective spinal surgery material ensures firm fixation and good bony fusion without neurological symptoms.

Area of Science:

  • Orthopedic Surgery
  • Neurosurgery
  • Biomaterials Science

Background:

  • Spinal cord compression is a risk during bone grafting near the spinal cord due to graft instability.
  • Autogeneic bone grafts are crucial for spinal fusion but can be prone to displacement.

Observation:

  • A novel technique involved mixing fibrin sealant with fine autogeneic bone fragments to create a paste-like graft material.
  • This mixture was used in various spinal fusion procedures, including posterolateral fusion, anterior fusion, and bone defect grafting.

Findings:

  • Solidification of the fibrin sealant resulted in firm fixation of the autogeneic bone grafts.
  • The technique led to good bony fusion with no instances of neurological symptoms related to graft instability.
  • No neurotoxicity was observed in any of the treated patients.

Related Experiment Videos

Implications:

  • Fibrin sealant is a safe and effective biomaterial for enhancing bone graft stability in spinal surgery.
  • This method mitigates the risk of spinal cord compression, improving patient outcomes.
  • The findings support the use of fibrin sealant as a valuable adjunct in spinal fusion procedures.