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Related Concept Videos

Coronary Circulation01:21

Coronary Circulation

The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
The Aorta01:14

The Aorta

The aorta is the largest artery in the human body. It originates from the left ventricle of the heart and extends down to the abdomen, where it splits into two smaller arteries. Structurally, it can be divided into four main parts: the ascending aorta, the aortic arch, the thoracic aorta, and the abdominal aorta.
The average diameter of the aorta is approximately 2-3 cm, but the size can vary depending on the section of the aorta and the individual's age, sex, and body size. The aorta is...
The Arch of Aorta01:10

The Arch of Aorta

The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...

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Related Experiment Video

Updated: Jul 16, 2026

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)
13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)

Published on: April 24, 2017

[Left circumflex coronary aneurysm with separated left main trunk].

Yoshitaka Takeda1, K Kawahito, M Tanaka

  • 1Department of Cardiovascular Surgery, Shonan-Kamakura General Hospital, Kamakura, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|March 14, 2007
PubMed
Summary

This case study details a rare coronary artery anomaly where the left main coronary artery bifurcated into separate left anterior descending and left circumflex origins. A significant aneurysm and stenosis in the left circumflex artery were successfully treated with ligation and bypass grafting.

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Murine Left Anterior Descending (LAD) Coronary Artery Ligation: An Improved and Simplified Model for Myocardial Infarction
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Area of Science:

  • Cardiology
  • Cardiovascular Surgery
  • Medical Imaging

Background:

  • Coronary artery anomalies are rare but can lead to significant cardiovascular events.
  • Congenital variations in coronary artery origins require accurate diagnosis for appropriate management.
  • Aneurysms and stenosis in coronary arteries pose a risk of myocardial infarction and sudden cardiac death.

Observation:

  • A 66-year-old male on hemodialysis presented with exertional dyspnea.
  • Coronary angiography and CT revealed separate origins for the left anterior descending (LAD) and left circumflex (LCx) coronary arteries from the left aortic sinus.
  • The LCx exhibited a 2 cm aneurysm with 99% proximal stenosis.

Findings:

  • The patient had a rare coronary anatomical variant: separated left main coronary trunks (LMT).
  • A significant left circumflex coronary aneurysm with critical stenosis was identified.
  • Successful surgical intervention involved aneurysm ligation and coronary artery bypass grafting.

Implications:

  • This case highlights the importance of advanced imaging in diagnosing complex coronary artery anomalies.
  • Surgical management of coronary aneurysms and stenosis in anomalous origins can be effective.
  • Understanding such variations is crucial for preventing adverse cardiac events in affected individuals.