Related Experiment Video
Updated: Jul 16, 2026

05:59
Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion
Published on: March 3, 2014
[Dissection of descending aorta with spinal paralysis]
Yutaka Kobayashi1, S Aomi, S Kihara
1Department of Cardiovascular Surgery, Tokyo Women's Medical University, Tokyo, Japan.
Kyobu Geka. the Japanese Journal of Thoracic Surgery
|March 14, 2007
Summary
Graft replacement effectively treated a descending aortic aneurysm causing spinal cord ischemia. This surgical approach can be a viable option for patients experiencing neurological deficits due to aortic disease.
Area of Science:
- Cardiovascular Surgery
- Neurology
- Vascular Surgery
Background:
- A 56-year-old male with a history of ascending aorta and total arch replacement for Stanford type A aortic dissection developed lower limb diplegia and vesicorectal dysfunction.
- Computed tomography (CT) revealed a large (80 mm) serpentine aneurysm in the descending aorta, extending from the left subclavian artery to the diaphragm.
Observation:
- Magnetic resonance imaging (MRI) was utilized to identify the Adamkiewicz artery, crucial for spinal cord blood supply, but it could not be visualized.
- The patient presented with significant neurological deficits, including paraplegia and bowel/bladder dysfunction, indicative of spinal cord ischemia.
Findings:
- Surgical intervention involved graft replacement of the descending aortic aneurysm.
- Reconstruction of the 8th intercostal artery using a branch graft was performed to potentially restore spinal cord perfusion.
- The patient experienced an uneventful postoperative recovery, with neurological symptoms potentially improving.
Implications:
- This case suggests that graft replacement, including targeted revascularization of spinal arteries like the 8th intercostal artery, can be an effective treatment for spinal cord ischemia secondary to descending aortic aneurysms.
- The successful management highlights the importance of considering complex aortic pathology and its neurological sequelae in surgical planning.
- Further research may explore the long-term efficacy and specific indications for such reconstructive techniques in preventing or treating spinal cord ischemia.
Related Concept Videos
Abdominal Aorta
Once the aorta traverses the diaphragmatic plane at the aortic hiatus, it is known as the abdominal aorta. This anatomical structure is positioned leftward of the spinal column, encased within a cocoon of adipose tissue behind the peritoneal cavity. It terminates at the L4 vertebra, where it splits into the common iliac arteries. Prior to this bifurcation, the abdominal aorta gives rise to several vital branches.
The celiac trunk, a singular artery, divides into the left gastric artery, which...
The celiac trunk, a singular artery, divides into the left gastric artery, which...
Spinal Cord: Cross-sectional Anatomy
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
Gray Matter and its Components
Central to the gray matter is...
Thoracic Aorta
The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...

