Jove
Visualize
Contact Us

Related Experiment Videos

Disposable jet nebulizers. How reliable are they?

G F Alvine1, P Rodgers, K M Fitzsimmons

  • 1College of Medicine, University of Iowa, Iowa City.

Chest
|February 1, 1992
PubMed
Summary

Some disposable jet nebulizer models exhibit poor quality control, leading to malfunctions and inconsistent aerosol particle size. Purchasing agents should prioritize reliability and conduct physical testing before selecting nebulizer models.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Report from the third international consensus meeting to harmonise core outcome measures for atopic eczema/dermatitis clinical trials (HOME).

The British journal of dermatology·2014
Same author

Kyathos at Aristophanes, Pax, 538-542; Lysistrata, 443-444 and [Aristotle] Problems, 890b7-38.

Classical philology·2007
Same author

Pseudomembranous colitis revisited: spectrum of imaging findings.

Clinical radiology·2006
Same author

Spatial and temporal bacterial quality of a lowland agricultural stream in northeast Scotland.

The Science of the total environment·2003
Same author

A hypothesis: self-propulsion in a wheelchair early after stroke might not be harmful.

Clinical rehabilitation·2003
Same author

Evaluation of particle size distribution of salmeterol administered via metered-dose inhaler with and without valved holding chambers.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2002
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Medical Devices
  • Respiratory Therapy
  • Quality Control

Background:

  • Disposable jet nebulizers are crucial for delivering inhaled medications.
  • Ensuring consistent performance and aerosol characteristics is vital for effective respiratory therapy.
  • Variability in nebulizer function can impact drug delivery and patient outcomes.

Purpose of the Study:

  • To evaluate the malfunction frequency, nebulization rate variability, and impact on aerosol particle size for disposable jet nebulizer models.
  • To identify potential quality control issues among different manufacturers of disposable nebulizers.

Main Methods:

  • Assessed eight disposable jet nebulizer models from six manufacturers.
  • Documented visual signs of malfunction, including droplet size, leakage, and air leaks.

Related Experiment Videos

  • Measured nebulization rate variability within models (57–129%).
  • Analyzed the relationship between nebulization rate variability and aerosol particle size distribution.

    • Main Results:

    • Four out of eight models displayed significant malfunctions.
    • Nebulization rate variability within models ranged widely, impacting particle size consistency.
    • Models with higher nebulization rate variability showed larger, inconsistent particle sizes.
    • Models with lower nebulization rate variability demonstrated more consistent particle sizes.

    Conclusions:

    • Significant quality control deficiencies exist among some disposable jet nebulizer manufacturers.
    • Nebulizer reliability and performance consistency are critical factors for purchasing agents.
    • Physical testing of multiple units per model is recommended to ensure reliable performance before procurement.