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Updated: May 27, 2026
16:19
High Throughput Single-cell and Multiple-cell Micro-encapsulation
Published on: June 15, 2012
Aspiration injury due to polyacrylamide.
A Jubran1, S D Greenberg, M D Solomon
1Division of Pulmonary and Critical Care Medicine, Edward Hines, Jr, Veterans Administration Hospital, Loyola University of Chicago Stritch School of Medicine, Maywood, Ill.
Chest
|February 1, 1992
Summary
Aspiration of polyacrylamide gel caused acute lung injury and death in a patient. This synthetic polymer
Area of Science:
- Toxicology
- Pulmonary Medicine
- Occupational Health
Background:
- Polyacrylamide is a synthetic polymer with widespread industrial applications.
- Acute lung injury from polyacrylamide aspiration has not been previously documented.
Observation:
- A 26-year-old man aspirated polyacrylamide gel while cleaning industrial equipment.
- The patient subsequently developed severe airway obstruction and lung parenchymal damage.
Findings:
- Autopsy revealed numerous polyacrylamide particles within the patient's lungs.
- Extensive bronchiolar and alveolar damage was observed, consistent with severe lung injury.
Implications:
- This case highlights a novel cause of acute lung injury.
- Occupational exposure to polyacrylamide may pose significant respiratory risks.
- Further research into polyacrylamide toxicity is warranted.
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