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Updated: Jul 16, 2026

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
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Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter

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Reactive oxygen species and DNA damage after ultrasound exposure

Katarzyna Milowska1, Teresa Gabryelak

  • 1Department of General Biophysics, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland. matsubara@bio.keio.ac.jp

Biomolecular Engineering
|March 14, 2007
PubMed

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In order to be passed through generations, genomic DNA must be undamaged and error-free. However, every day, DNA in a cell undergoes several thousand to a million damaging events by natural causes and external factors. Ionizing radiation such as UV rays, free radicals produced during cellular respiration, and hydrolytic damage from metabolic reactions can alter the structure of DNA. Damages caused include single-base alteration, base dimerization, chain breaks, and cross-linkage.
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