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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Detecting visual function abnormalities using the Swedish interactive threshold algorithm and matrix perimetry in
Lisandro M Sakata1, Julio Deleon-Ortega, Stella N Arthur
1Department of Ophthalmology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Archives of Ophthalmology (Chicago, Ill. : 1960)
|March 14, 2007
Summary
Frequency-doubling perimetry (FDP-Matrix) detected more visual field abnormalities in glaucomatous-appearing optic discs (GAOD) than standard automated perimetry (SAP-SITA), though not significantly. Combining tests may enhance glaucoma detection.
Area of Science:
- Ophthalmology
- Visual Neuroscience
Background:
- Glaucomatous-appearing optic discs (GAOD) present a diagnostic challenge.
- Accurate visual field testing is crucial for early glaucoma detection.
Purpose of the Study:
- To compare the diagnostic capabilities of 24-2 frequency-doubling perimetry (FDP-Matrix) versus standard automated perimetry with Swedish interactive threshold algorithm (SAP-SITA).
- To assess the detection rates of visual function abnormalities in patients with GAOD using these two perimetry methods.
Main Methods:
- An observational case-control study involving 80 patients with GAOD and 54 controls.
- Abnormal visual function was defined by consistent abnormalities in two examinations using established criteria (Glaucoma Hemifield Test, pattern standard deviation, pattern deviation probability plot).
Main Results:
- FDP-Matrix detected abnormalities in 51% of GAOD eyes, compared to 44% with SAP-SITA (P = .26).
- Both tests identified 11% of healthy eyes as abnormal.
- Moderate agreement (kappa = 0.49) was observed, with only 35% of GAOD eyes flagged by both tests.
Conclusions:
- FDP-Matrix showed a trend towards detecting more visual function abnormalities in GAOD eyes than SAP-SITA.
- Each perimetry technique identified distinct subsets of GAOD eyes.
- Combining FDP-Matrix and SAP-SITA may offer improved detection of visual dysfunction in glaucoma patients.
