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Updated: Jul 16, 2026

Transthoracic Echocardiography in Mice
Published on: May 28, 2010
[Evaluation of echocardiographic left ventricular wall motion analysis supported by internet picture viewing system]
Yutaka Hirano1, Shin-Ichiro Ikuta, Manabu Nakano
1Division of Cardiology, Department of Internal Medicine, Kinki University School of Medicine, Osaka. yuhirano-circ@umin.ac.jp
Background:
Assessment of deterioration of regional wall motion by echocardiography is not only subjective but also features difficulties with interobserver agreement. Progress in digital communication technology has made it possible to send video images from a distant location via the Internet.
Objectives:
The possibility of evaluating left ventricular wall motion using video images sent via the Internet to distant institutions was evaluated.
Methods:
Twenty-two subjects were randomly selected. Four sets of video images (parasternal long-axis view, parasternal short-axis view, apical four-chamber view, and apical two-chamber view) were taken for one cardiac cycle. The images were sent via the Internet to two institutions (observer C in facility A and observers D and E in facility B) for evaluation. Great care was taken to prevent disclosure of patient information to these observers. Parasternal long-axis images were divided into four segments, and the parasternal short-axis view, apical four-chamber view, and apical two-chamber view were divided into six segments. One of the following assessments, normokinesis, hypokinesis, akinesis, or dyskinesis, was assigned to each segment. The interobserver rates of agreement in judgments between observers C and D, observers C and E, and intraobserver agreement rate (for observer D) were calculated.
Results:
The rate of interobserver agreement was 85.7% (394/460 segments; Kappa = 0.65) between observers C and D, 76.7% (353/460 segments; Kappa = 0.39) between observers D and E, and 76.3% (351/460 segments; Kappa = 0.36)between observers C and E, and intraobserver agreement was 94.3% (434/460; Kappa = 0.86). Segments of difference judgments between observers C and D were normokinesis-hypokinesis; 62.1%, hypokinesis-akinesis; 33.3%, akinesis-dyskinesis; 3.0%, and normokinesis-akinesis; 1.5%.
Conclusions:
Wall motion can be evaluated at remote institutions via the Internet.
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